The Compvide Complement Platform
Compvide's platform integrates complement biology expertise, functional assay design, and rigorous sample integrity control to generate reliable, physiologically relevant data for translational research, drug development, and diagnostic innovation.
Complement Assay Platform
At the core of Compvide is a functional complement assay platform spanning all three activation pathways and terminal pathway biology.
This comprehensive pathway coverage enables mechanistic assessment of complement activation and inhibition rather than reliance on indirect or surrogate readouts.
Functional & High-Serum Testing
We design assays to reflect true biological function under conditions that preserve native complement behavior.
- High-serum and physiologic testing conditions to maintain biologically relevant activity
- Pathway-specific activation and inhibition readouts for mechanistic clarity
- Functional relevance over convenience assays, ensuring data supports translational decision-making
Introducing CIMED™
Complement Inhibition Monitoring & Efficacy Determination
CIMED™ is Compvide's proprietary diagnostic platform designed to assess complement activity and therapeutic inhibition under physiologic serum conditions. Built on Compvide's deep expertise in functional complement assay development, CIMED™ supports a scalable approach to drug monitoring, translational research, and future clinical diagnostics.
Currently supplied for Research Use Only (RUO), with a long-term vision toward scaled diagnostic monitoring and clinical diagnostics.
Our quality systems support:
- Preservation of functional complement activity
- Reproducibility across studies and time points
- Increased confidence in assay results and downstream interpretation
Multi-Species Capability
Supporting translational continuity from preclinical to clinical studies
Sample Integrity & Quality Systems
Complement activity is highly sensitive to sample collection, preparation, and handling. Improper workflows can lead to unintended activation and depletion, compromising functional results.
Compvide has developed specialized preparation, handling, and quality control protocols designed to preserve native complement activity and minimize artifactual activation.
Complement Assays & Scientific Services
Compvide provides standard and custom complement assay services supporting drug discovery, preclinical development, and translational research. Our services are built on functional relevance, pathway specificity, and rigorous sample handling.
Functional Complement Assays
We perform pathway-specific functional assays in human and animal samples, enabling mechanistic assessment of complement activation and inhibition.
Measured functional outputs:
- • C4 activation
- • C3 activation
- • Terminal pathway activity (C5b-9)
- • Hemolytic assays (CH50, APH50)
Clinical & Translational Studies
We support complement-focused programs from preclinical models through clinical study execution, providing data that connects mechanism to outcome.
Services include:
- • Clinical study sample testing
- • Functional complement monitoring
- • Translational readouts across species
- • Support for complement-targeted programs
Complement Biomarker Analysis
We measure complement activation biomarkers using fully validated assays, supporting pharmacodynamic and mechanistic studies.
Biomarkers include:
- • C3a, C4a, C5a
- • Ba
- • Soluble C5b-9
Custom Assay Development
We develop and validate custom complement assays tailored to specific targets, pathways, or therapeutic modalities.
Custom assays are designed in collaboration with our partners to align with program-specific scientific and translational goals.
Capabilities include assays for: